Big Book TC Test 1, Section 1, Q.3 (

There are, as yet, no vegetation types or ecosystems whose study has been ------- to the extent that they no longer ------- ecologists.
(A) perfected . . hinder
(B) exhausted . .interest
(C) prolonged…require
(D) prevented…challenge
(E) delayed . . benefit

Is there a way to do this effectively via the math strategy? Double negatives always confuse me! Thanks!